Top Cited Papers (WoS Core)
泛素化 Top 10 高被引论文
按 WoS Core Collection 总被引次数排序，覆盖方法学、机制研究与疾病转化。每条论文提供 DOI 直链 + 摘要前 280 字 + 前 4 位作者。
#1582 引用
NATURE PROTOCOLS · 2018 · Vol.13 (3) · p.530-550
Zhang, XF; Smits, AH; van Tilburg, GBA; Ovaa, H; et al.
biquitin-binding proteins play an important role in eukaryotes by translating differently linked polyubiquitin chains into proper cellular responses. Current knowledge about ubiquitin-binding proteins and ubiquitin linkage-selective interactions is mostly based on case-by-case st…
#2275 引用
ONCOGENE · 2023 · Vol.42 (2) · p.83-98
Li, DB; Wang, YH; Dong, C; Chen, T; et al.
Metastasis is an important factor contributing to poor prognosis in patients with gastric cancer; yet, the molecular mechanism leading to this cell behavior is still not well understood. In this study, we explored the role of cysteine protease inhibitor SN (Cystatin SN, CST1) in …
#3217 引用
SIGNAL TRANSDUCTION AND TARGETED THERAPY · 2023 · Vol.8 (1)
Wu, XM; Xu, MY; Geng, MY; Chen, S; et al.
The ever-increasing prevalence of noncommunicable diseases (NCDs) represents a major public health burden worldwide. The most common form of NCD is metabolic diseases, which affect people of all ages and usually manifest their pathobiology through life-threatening cardiovascular …
#4217 引用
SIGNAL TRANSDUCTION AND TARGETED THERAPY · 2023 · Vol.8 (1)
Wu, XM; Xu, MY; Geng, MY; Chen, S; et al.
The ever-increasing prevalence of noncommunicable diseases (NCDs) represents a major public health burden worldwide. The most common form of NCD is metabolic diseases, which affect people of all ages and usually manifest their pathobiology through life-threatening cardiovascular …
#5217 引用
SIGNAL TRANSDUCTION AND TARGETED THERAPY · 2023 · Vol.8 (1)
Wu, XM; Xu, MY; Geng, MY; Chen, S; et al.
The ever-increasing prevalence of noncommunicable diseases (NCDs) represents a major public health burden worldwide. The most common form of NCD is metabolic diseases, which affect people of all ages and usually manifest their pathobiology through life-threatening cardiovascular …
#6217 引用
SIGNAL TRANSDUCTION AND TARGETED THERAPY · 2023 · Vol.8 (1)
Wu, XM; Xu, MY; Geng, MY; Chen, S; et al.
The ever-increasing prevalence of noncommunicable diseases (NCDs) represents a major public health burden worldwide. The most common form of NCD is metabolic diseases, which affect people of all ages and usually manifest their pathobiology through life-threatening cardiovascular …
#7217 引用
SIGNAL TRANSDUCTION AND TARGETED THERAPY · 2023 · Vol.8 (1)
Wu, XM; Xu, MY; Geng, MY; Chen, S; et al.
The ever-increasing prevalence of noncommunicable diseases (NCDs) represents a major public health burden worldwide. The most common form of NCD is metabolic diseases, which affect people of all ages and usually manifest their pathobiology through life-threatening cardiovascular …
#8194 引用
JOURNAL OF GENETICS AND GENOMICS · 2017 · Vol.44 (5) · p.243-250
Xu, HD; Zhou, JQ; Lin, SF; Deng, WK; et al.
Post-translational modifications (PTMs) occurring at protein lysine residues, or protein lysine modifications (PLMs), play critical roles in regulating biological processes. Due to the explosive expansion of the amount of PLM substrates and the discovery of novel PLM types, here …
#9176 引用
OPEN BIOLOGY · 2017 · Vol.7 (10)
Yang, YF; He, Y; Wang, XX; Liang, ZW; et al.
SUMOylation, as a post-translational modification, plays essential roles in various biological functions including cell growth, migration, cellular responses to stress and tumorigenesis. The imbalance of SUMOylation and deSUMOylation has been associated with the occurrence and pr…
#10155 引用
REDOX BIOLOGY · 2023 · Vol.62
Zhu, J; Sun, RP; Sun, KQ; Yan, C; et al.
Increasing studies have reported that intervertebral disc degeneration (IVDD) is the main contributor and independent risk factor for low back pain (LBP), it would be, therefore, enlightening that investigating the exact pathogenesis of IVDD and developing target-specific molecul…