Top Cited Papers (WoS Core)
棕榈酰化 Top 10 高被引论文
按 WoS Core Collection 总被引次数排序，覆盖方法学、机制研究与疾病转化。每条论文提供 DOI 直链 + 摘要前 280 字 + 前 4 位作者。
#1391 引用
PHARMACOLOGICAL REVIEWS · 2022 · Vol.74 (3) · p.506-551
Dambrova, M; Makrecka-Kuka, M; Kuka, J; Vilskersts, R; et al.
Acylcarnitines are fatty acid metabolites that play important roles in many cellular energy metabolism pathways. They have historically been used as important diagnostic markers for inborn errors of fatty acid oxidation and are being intensively studied as markers of energy metab…
#2252 引用
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS · 2018 · Vol.19 (1) · p.93-106
Knottnerus, SJG; Bleeker, JC; Wüst, RCI; Ferdinandusse, S; et al.
Mitochondrial fatty acid oxidation is an essential pathway for energy production, especially during prolonged fasting and sub-maximal exercise. Long-chain fatty acids are the most abundant fatty acids in the human diet and in body stores, and more than 15 enzymes are involved in …
#3190 引用
SIGNAL TRANSDUCTION AND TARGETED THERAPY · 2022 · Vol.7 (1)
Shang, S; Liu, J; Hua, F
Metabolic reprogramming is involved in the pathogenesis of not only cancers but also neurodegenerative diseases, cardiovascular diseases, and infectious diseases. With the progress of metabonomics and proteomics, metabolites have been found to affect protein acylations through pr…
#4190 引用
SIGNAL TRANSDUCTION AND TARGETED THERAPY · 2022 · Vol.7 (1)
Shang, S; Liu, J; Hua, F
Metabolic reprogramming is involved in the pathogenesis of not only cancers but also neurodegenerative diseases, cardiovascular diseases, and infectious diseases. With the progress of metabonomics and proteomics, metabolites have been found to affect protein acylations through pr…
#5190 引用
SIGNAL TRANSDUCTION AND TARGETED THERAPY · 2022 · Vol.7 (1)
Shang, S; Liu, J; Hua, F
Metabolic reprogramming is involved in the pathogenesis of not only cancers but also neurodegenerative diseases, cardiovascular diseases, and infectious diseases. With the progress of metabonomics and proteomics, metabolites have been found to affect protein acylations through pr…
#6187 引用
CELL RESEARCH · 2007 · Vol.17 (12) · p.1030-1040
Shi, LH; Bielawski, J; Mu, JY; Dong, HL; et al.
Sphingolipids have been suggested to act as second messengers for an array of cellular signaling activities in plant cells, including stress responses and programmed cell death (PCD). However, the mechanisms underpinning these processes are not well understood. Here, we report th…
#7151 引用
SCIENCE IMMUNOLOGY · 2024 · Vol.9 (94)
Balasubramanian, A; Hsu, AY; Ghimire, L; Tahir, M; et al.
Plasma membrane perforation elicited by caspase cleavage of the gasdermin D (GSDMD) N-terminal domain (GSDMD-NT) triggers pyroptosis. The mechanisms underlying GSDMD membrane translocation and pore formation are not fully understood. Here, using a proteomic approach, we identifie…
#8121 引用
DEVELOPMENTAL CELL · 2018 · Vol.47 (4) · p.479-+
Ernst, AM; Syed, SA; Zaki, O; Bottanelli, F; et al.
While retrograde cargo selection in the Golgi is known to depend on specific signals, it is unknown whether anterograde cargo is sorted, and antero-grade signals have not been identified. We suggest here that S-palmitoylation of anterograde cargo at the Golgi membrane interface i…
#9116 引用
NATURE COMMUNICATIONS · 2024 · Vol.15 (1)
Ni, H; Wang, YN; Yao, K; Wang, L; et al.
Toll-like receptor 9 (TLR9) recognizes self-DNA and plays intricate roles in systemic lupus erythematosus (SLE). However, the molecular mechanism regulating the endosomal TLR9 response is incompletely understood. Here, we report that palmitoyl-protein thioesterase 1 (PPT1) regula…
#10116 引用
NATURE COMMUNICATIONS · 2024 · Vol.15 (1)
Ni, H; Wang, YN; Yao, K; Wang, L; et al.
Toll-like receptor 9 (TLR9) recognizes self-DNA and plays intricate roles in systemic lupus erythematosus (SLE). However, the molecular mechanism regulating the endosomal TLR9 response is incompletely understood. Here, we report that palmitoyl-protein thioesterase 1 (PPT1) regula…